X-Men Origins: Wolverine actor Liev Schreiber explained the reason for this Deadpool and Wolverine It didn't feature the return of Sabretooth in the MCU. Schreiber is the second actor after Tyler Mane to portray Wolverine's long-time rival Sabretooth in a live-action film. Despite boasting more screen time X-Men Origins: Wolverinebut Schreiber was not among the many Deadpool and Wolverine cameos.
When asked about his absence in an interview with Collider, Schreiber said he was happy to pass on the role after seeing the physical demands met by former co-star Hugh Jackman, although he was moved by fans clamoring for his return. Here is his full quote:
Honestly, getting your body to this level is a lot of work. I know I'm looking at Hugh [Jackman] he readied himself and I thought I'd better sit out.
Source: Collider